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1.

Embracing cancer complexity: Hallmarks of systemic disease.

Swanton, Charles; Bernard, Elsa; Abbosh, Chris; André, Fabrice; Auwerx, Johan; Balmain, Allan; Bar-Sagi, Dafna; Bernards, René; Bullman, Susan; DeGregori, James; Elliott, Catherine; Erez, Ayelet; Evan, Gerard; Febbraio, Mark A; Hidalgo, Andrés; Jamal-Hanjani, Mariam; Joyce, Johanna A; Kaiser, Matthew; Lamia, Katja; Locasale, Jason W; Loi, Sherene; Malanchi, Ilaria; Merad, Miriam; Musgrave, Kathryn; Patel, Ketan J; Quezada, Sergio; Wargo, Jennifer A; Weeraratna, Ashani; White, Eileen; Winkler, Frank; Wood, John N; Vousden, Karen H; Hanahan, Douglas.

Cell ; 187(7): 1589-1616, 2024 Mar 28.

Artículo en Inglés | MEDLINE | ID: mdl-38552609

2.

Breaking down a gut-to-brain circuit that prevents malabsorption.

Jarvie, Brooke C; Knight, Zachary A.

Cell ; 185(14): 2393-2395, 2022 07 07.

Artículo en Inglés | MEDLINE | ID: mdl-35803241

3.

Local hyperthermia therapy induces browning of white fat and treats obesity.

Li, Yu; Wang, Dongmei; Ping, Xiaodan; Zhang, Yankang; Zhang, Ting; Wang, Li; Jin, Li; Zhao, Wenjun; Guo, Mingwei; Shen, Fei; Meng, Meiyao; Chen, Xin; Zheng, Ying; Wang, Jiqiu; Li, Dali; Zhang, Qiang; Hu, Cheng; Xu, Lingyan; Ma, Xinran.

Cell ; 185(6): 949-966.e19, 2022 03 17.

Artículo en Inglés | MEDLINE | ID: mdl-35247329

4.

Microbiota imbalance induced by dietary sugar disrupts immune-mediated protection from metabolic syndrome.

Kawano, Yoshinaga; Edwards, Madeline; Huang, Yiming; Bilate, Angelina M; Araujo, Leandro P; Tanoue, Takeshi; Atarashi, Koji; Ladinsky, Mark S; Reiner, Steven L; Wang, Harris H; Mucida, Daniel; Honda, Kenya; Ivanov, Ivaylo I.

Cell ; 185(19): 3501-3519.e20, 2022 09 15.

Artículo en Inglés | MEDLINE | ID: mdl-36041436

5.

Architecture of the outbred brown fat proteome defines regulators of metabolic physiology.

Xiao, Haopeng; Bozi, Luiz H M; Sun, Yizhi; Riley, Christopher L; Philip, Vivek M; Chen, Mandy; Li, Jiaming; Zhang, Tian; Mills, Evanna L; Emont, Margo P; Sun, Wenfei; Reddy, Anita; Garrity, Ryan; Long, Jiani; Becher, Tobias; Vitas, Laura Potano; Laznik-Bogoslavski, Dina; Ordonez, Martha; Liu, Xinyue; Chen, Xiong; Wang, Yun; Liu, Weihai; Tran, Nhien; Liu, Yitong; Zhang, Yang; Cypess, Aaron M; White, Andrew P; He, Yuchen; Deng, Rebecca; Schöder, Heiko; Paulo, Joao A; Jedrychowski, Mark P; Banks, Alexander S; Tseng, Yu-Hua; Cohen, Paul; Tsai, Linus T; Rosen, Evan D; Klein, Samuel; Chondronikola, Maria; McAllister, Fiona E; Van Bruggen, Nick; Huttlin, Edward L; Spiegelman, Bruce M; Churchill, Gary A; Gygi, Steven P; Chouchani, Edward T.

Cell ; 185(24): 4654-4673.e28, 2022 11 23.

Artículo en Inglés | MEDLINE | ID: mdl-36334589

6.

Spatial proteogenomics reveals distinct and evolutionarily conserved hepatic macrophage niches.

Guilliams, Martin; Bonnardel, Johnny; Haest, Birthe; Vanderborght, Bart; Wagner, Camille; Remmerie, Anneleen; Bujko, Anna; Martens, Liesbet; Thoné, Tinne; Browaeys, Robin; De Ponti, Federico F; Vanneste, Bavo; Zwicker, Christian; Svedberg, Freya R; Vanhalewyn, Tineke; Gonçalves, Amanda; Lippens, Saskia; Devriendt, Bert; Cox, Eric; Ferrero, Giuliano; Wittamer, Valerie; Willaert, Andy; Kaptein, Suzanne J F; Neyts, Johan; Dallmeier, Kai; Geldhof, Peter; Casaert, Stijn; Deplancke, Bart; Ten Dijke, Peter; Hoorens, Anne; Vanlander, Aude; Berrevoet, Frederik; Van Nieuwenhove, Yves; Saeys, Yvan; Saelens, Wouter; Van Vlierberghe, Hans; Devisscher, Lindsey; Scott, Charlotte L.

Cell ; 185(2): 379-396.e38, 2022 01 20.

Artículo en Inglés | MEDLINE | ID: mdl-35021063

7.

Metabolic consequences of obesity and type 2 diabetes: Balancing genes and environment for personalized care.

Pillon, Nicolas J; Loos, Ruth J F; Marshall, Sally M; Zierath, Juleen R.

Cell ; 184(6): 1530-1544, 2021 03 18.

Artículo en Inglés | MEDLINE | ID: mdl-33675692

8.

Macrophage function in adipose tissue homeostasis and metabolic inflammation.

Chavakis, Triantafyllos; Alexaki, Vasileia Ismini; Ferrante, Anthony W.

Nat Immunol ; 24(5): 757-766, 2023 05.

Artículo en Inglés | MEDLINE | ID: mdl-37012544

9.

Fighting for Fat: Gluttonous Tumors and Starved T Cells.

Goodman, Joshua H; Ferrante, Anthony W.

Cell ; 183(7): 1739-1741, 2020 12 23.

Artículo en Inglés | MEDLINE | ID: mdl-33357398

10.

Identification of ALK in Thinness.

Orthofer, Michael; Valsesia, Armand; Mägi, Reedik; Wang, Qiao-Ping; Kaczanowska, Joanna; Kozieradzki, Ivona; Leopoldi, Alexandra; Cikes, Domagoj; Zopf, Lydia M; Tretiakov, Evgenii O; Demetz, Egon; Hilbe, Richard; Boehm, Anna; Ticevic, Melita; Nõukas, Margit; Jais, Alexander; Spirk, Katrin; Clark, Teleri; Amann, Sabine; Lepamets, Maarja; Neumayr, Christoph; Arnold, Cosmas; Dou, Zhengchao; Kuhn, Volker; Novatchkova, Maria; Cronin, Shane J F; Tietge, Uwe J F; Müller, Simone; Pospisilik, J Andrew; Nagy, Vanja; Hui, Chi-Chung; Lazovic, Jelena; Esterbauer, Harald; Hagelkruys, Astrid; Tancevski, Ivan; Kiefer, Florian W; Harkany, Tibor; Haubensak, Wulf; Neely, G Gregory; Metspalu, Andres; Hager, Jorg; Gheldof, Nele; Penninger, Josef M.

Cell ; 181(6): 1246-1262.e22, 2020 06 11.

Artículo en Inglés | MEDLINE | ID: mdl-32442405

11.

SnapShot: FABP Functions.

Li, Bing; Hao, Jiaqing; Zeng, Jun; Sauter, Edward R.

Cell ; 182(4): 1066-1066.e1, 2020 08 20.

Artículo en Inglés | MEDLINE | ID: mdl-32822569

12.

Endocrine-Exocrine Signaling Drives Obesity-Associated Pancreatic Ductal Adenocarcinoma.

Chung, Katherine Minjee; Singh, Jaffarguriqbal; Lawres, Lauren; Dorans, Kimberly Judith; Garcia, Cathy; Burkhardt, Daniel B; Robbins, Rebecca; Bhutkar, Arjun; Cardone, Rebecca; Zhao, Xiaojian; Babic, Ana; Vayrynen, Sara A; Dias Costa, Andressa; Nowak, Jonathan A; Chang, Daniel T; Dunne, Richard F; Hezel, Aram F; Koong, Albert C; Wilhelm, Joshua J; Bellin, Melena D; Nylander, Vibe; Gloyn, Anna L; McCarthy, Mark I; Kibbey, Richard G; Krishnaswamy, Smita; Wolpin, Brian M; Jacks, Tyler; Fuchs, Charles S; Muzumdar, Mandar Deepak.

Cell ; 181(4): 832-847.e18, 2020 05 14.

Artículo en Inglés | MEDLINE | ID: mdl-32304665

13.

A MicroRNA Linking Human Positive Selection and Metabolic Disorders.

Wang, Lifeng; Sinnott-Armstrong, Nasa; Wagschal, Alexandre; Wark, Abigail R; Camporez, Joao-Paulo; Perry, Rachel J; Ji, Fei; Sohn, Yoojin; Oh, Justin; Wu, Su; Chery, Jessica; Moud, Bahareh Nemati; Saadat, Alham; Dankel, Simon N; Mellgren, Gunnar; Tallapragada, Divya Sri Priyanka; Strobel, Sophie Madlen; Lee, Mi-Jeong; Tewhey, Ryan; Sabeti, Pardis C; Schaefer, Anne; Petri, Andreas; Kauppinen, Sakari; Chung, Raymond T; Soukas, Alexander; Avruch, Joseph; Fried, Susan K; Hauner, Hans; Sadreyev, Ruslan I; Shulman, Gerald I; Claussnitzer, Melina; Näär, Anders M.

Cell ; 183(3): 684-701.e14, 2020 10 29.

Artículo en Inglés | MEDLINE | ID: mdl-33058756

14.

Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity.

Ringel, Alison E; Drijvers, Jefte M; Baker, Gregory J; Catozzi, Alessia; García-Cañaveras, Juan C; Gassaway, Brandon M; Miller, Brian C; Juneja, Vikram R; Nguyen, Thao H; Joshi, Shakchhi; Yao, Cong-Hui; Yoon, Haejin; Sage, Peter T; LaFleur, Martin W; Trombley, Justin D; Jacobson, Connor A; Maliga, Zoltan; Gygi, Steven P; Sorger, Peter K; Rabinowitz, Joshua D; Sharpe, Arlene H; Haigis, Marcia C.

Cell ; 183(7): 1848-1866.e26, 2020 12 23.

Artículo en Inglés | MEDLINE | ID: mdl-33301708

15.

CD81 Controls Beige Fat Progenitor Cell Growth and Energy Balance via FAK Signaling.

Oguri, Yasuo; Shinoda, Kosaku; Kim, Hyeonwoo; Alba, Diana L; Bolus, W Reid; Wang, Qiang; Brown, Zachary; Pradhan, Rachana N; Tajima, Kazuki; Yoneshiro, Takeshi; Ikeda, Kenji; Chen, Yong; Cheang, Rachel T; Tsujino, Kazuyuki; Kim, Caroline R; Greiner, Vanille Juliette; Datta, Ritwik; Yang, Christopher D; Atabai, Kamran; McManus, Michael T; Koliwad, Suneil K; Spiegelman, Bruce M; Kajimura, Shingo.

Cell ; 182(3): 563-577.e20, 2020 08 06.

Artículo en Inglés | MEDLINE | ID: mdl-32615086

16.

A Tale of Three Systems: Toward a Neuroimmunoendocrine Model of Obesity.

O'Brien, Conan J O; Haberman, Emma R; Domingos, Ana I.

Annu Rev Cell Dev Biol ; 37: 549-573, 2021 10 06.

Artículo en Inglés | MEDLINE | ID: mdl-34613819

17.

Polygenic Risk Scores Expand to Obesity.

Torkamani, Ali; Topol, Eric.

Cell ; 177(3): 518-520, 2019 04 18.

Artículo en Inglés | MEDLINE | ID: mdl-31002792

18.

Polygenic Prediction of Weight and Obesity Trajectories from Birth to Adulthood.

Khera, Amit V; Chaffin, Mark; Wade, Kaitlin H; Zahid, Sohail; Brancale, Joseph; Xia, Rui; Distefano, Marina; Senol-Cosar, Ozlem; Haas, Mary E; Bick, Alexander; Aragam, Krishna G; Lander, Eric S; Smith, George Davey; Mason-Suares, Heather; Fornage, Myriam; Lebo, Matthew; Timpson, Nicholas J; Kaplan, Lee M; Kathiresan, Sekar.

Cell ; 177(3): 587-596.e9, 2019 04 18.

Artículo en Inglés | MEDLINE | ID: mdl-31002795

19.

Human Gain-of-Function MC4R Variants Show Signaling Bias and Protect against Obesity.

Lotta, Luca A; Mokrosinski, Jacek; Mendes de Oliveira, Edson; Li, Chen; Sharp, Stephen J; Luan, Jian'an; Brouwers, Bas; Ayinampudi, Vikram; Bowker, Nicholas; Kerrison, Nicola; Kaimakis, Vasileios; Hoult, Diana; Stewart, Isobel D; Wheeler, Eleanor; Day, Felix R; Perry, John R B; Langenberg, Claudia; Wareham, Nicholas J; Farooqi, I Sadaf.

Cell ; 177(3): 597-607.e9, 2019 04 18.

Artículo en Inglés | MEDLINE | ID: mdl-31002796

20.

Lipid-Associated Macrophages Control Metabolic Homeostasis in a Trem2-Dependent Manner.

Jaitin, Diego Adhemar; Adlung, Lorenz; Thaiss, Christoph A; Weiner, Assaf; Li, Baoguo; Descamps, Hélène; Lundgren, Patrick; Bleriot, Camille; Liu, Zhaoyuan; Deczkowska, Aleksandra; Keren-Shaul, Hadas; David, Eyal; Zmora, Niv; Eldar, Shai Meron; Lubezky, Nir; Shibolet, Oren; Hill, David A; Lazar, Mitchell A; Colonna, Marco; Ginhoux, Florent; Shapiro, Hagit; Elinav, Eran; Amit, Ido.

Cell ; 178(3): 686-698.e14, 2019 07 25.

Artículo en Inglés | MEDLINE | ID: mdl-31257031

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